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Boyang Yu Selected Research

ruscogenin

3/2022Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
1/2022Ruscogenin Alleviates Deep Venous Thrombosis and Pulmonary Embolism Induced by Inferior Vena Cava Stenosis Inhibiting MEK/ERK/Egr-1/TF Signaling Pathway in Mice.
1/2021Mechanisms dissection of the combination GRS derived from ShengMai preparations for the treatment of myocardial ischemia/reperfusion injury.
1/2020The Traditional Chinese Medicine Compound, GRS, Alleviates Blood-Brain Barrier Dysfunction.
1/2018DT-13 ameliorates TNF-α-induced nitric oxide production in the endothelium in vivo and in vitro.
1/2017DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling Pathway.
8/2016Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway.
1/2015The saponin DT-13 attenuates tumor necrosis factor-α-induced vascular inflammation associated with Src/NF-кB/MAPK pathway modulation.
8/2013Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse model of experimental stroke.
1/2012Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB.
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Boyang Yu Research Topics

Disease

13Inflammation (Inflammations)
01/2022 - 07/2005
12Brain Ischemia (Cerebral Ischemia)
01/2022 - 06/2008
12Neoplasms (Cancer)
01/2020 - 11/2010
9Cardiovascular Diseases (Cardiovascular Disease)
03/2022 - 03/2011
9Reperfusion Injury
12/2021 - 06/2008
8Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2022 - 08/2013
7Myocardial Ischemia (Ischemic Heart Diseases)
03/2022 - 11/2016
7Infarction (Infarctions)
01/2022 - 08/2013
7Thrombosis (Thrombus)
02/2020 - 06/2006
6Acute Lung Injury
01/2022 - 01/2012
6Neoplasm Metastasis (Metastasis)
01/2021 - 01/2010
6Breast Neoplasms (Breast Cancer)
01/2021 - 12/2009
6Ischemia
11/2018 - 03/2005
4Venous Thrombosis (Deep-Vein Thrombosis)
01/2022 - 09/2005
4Heart Failure
05/2019 - 05/2016
4Edema (Dropsy)
08/2016 - 07/2005
3Hypersensitivity (Allergy)
01/2022 - 01/2018
3Cerebrovascular Disorders (Cerebrovascular Occlusion)
01/2022 - 01/2016
3Pheochromocytoma
01/2022 - 01/2016
3type 2C Congenital disorder of glycosylation
01/2022 - 01/2017
3Myocardial Infarction
01/2021 - 01/2019
3Fibrosis (Cirrhosis)
01/2020 - 03/2019
3Brain Infarction
08/2016 - 06/2008
3Sepsis (Septicemia)
08/2016 - 08/2006
3Pulmonary Edema
08/2016 - 01/2012
3Hypoxia (Hypoxemia)
04/2013 - 01/2010
2Dysmenorrhea (Menstrual Pain)
05/2022 - 10/2020
2Brain Injuries (Brain Injury)
01/2021 - 01/2021
2Ischemic Stroke
01/2020 - 01/2017
2Herpes Zoster
01/2020 - 01/2016
2Mitochondrial Diseases (Mitochondrial Disease)
01/2019 - 01/2017
2Pain (Aches)
01/2019 - 01/2018
2Leukemia
09/2017 - 09/2011
2Anaphylaxis (Anaphylactic Shock)
09/2017 - 01/2017
2Central Nervous System Diseases (CNS Diseases)
01/2017 - 01/2016
2Stroke (Strokes)
05/2016 - 08/2013
2Melanoma (Melanoma, Malignant)
07/2015 - 08/2012

Drug/Important Bio-Agent (IBA)

13ruscogeninIBA
03/2022 - 07/2005
11Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2010
10radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA
01/2022 - 12/2015
8Glucose (Dextrose)FDA LinkGeneric
03/2022 - 01/2016
8Oxygen (Dioxygen)IBA
03/2022 - 01/2016
8yi-qi-fu-maiIBA
01/2022 - 01/2016
8SaponinsIBA
01/2020 - 12/2006
7Pharmaceutical PreparationsIBA
05/2022 - 11/2010
7Neuroprotective AgentsIBA
01/2022 - 10/2014
7PowdersIBA
01/2020 - 01/2016
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2020 - 09/2005
6Thromboplastin (Tissue Factor)IBA
02/2020 - 01/2010
5blebbistatinIBA
01/2022 - 07/2015
5LipopolysaccharidesIBA
02/2020 - 05/2008
4ginsenoside Rb1IBA
03/2022 - 12/2015
4Myosin Type IIIBA
01/2022 - 01/2017
4Hematoxylin (Haematoxylon)IBA
01/2021 - 03/2019
4Evans Blue (Blue, Evans)FDA Link
01/2021 - 06/2008
4Eosine Yellowish-(YS) (Eosin)IBA
01/2021 - 03/2019
4CarrageenanIBA
05/2008 - 07/2005
3Therapeutic UsesIBA
01/2022 - 01/2020
3schizandrinIBA
01/2021 - 12/2015
3NF-kappa B (NF-kB)IBA
01/2021 - 06/2008
3Myosin Heavy Chains (Myosin Heavy Chain)IBA
01/2021 - 07/2015
3Biological ProductsIBA
01/2020 - 01/2012
3Messenger RNA (mRNA)IBA
01/2018 - 01/2010
3ophiopogonin DIBA
07/2015 - 07/2005
2Oxytocin (Pitocin)FDA LinkGeneric
05/2022 - 01/2015
2Cisplatin (Platino)FDA LinkGeneric
01/2022 - 02/2016
2TriterpenesIBA
01/2022 - 01/2020
2CateninsIBA
01/2022 - 05/2019
2AcidsIBA
10/2021 - 05/2016
2Anti-Allergic Agents (Antiallergic Agents)IBA
10/2021 - 01/2020
2Matrix Metalloproteinases (MMPs)IBA
01/2021 - 01/2020
2triphenyltetrazoliumIBA
01/2021 - 01/2021
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
04/2020 - 12/2016
2Creatine Kinase (Creatine Phosphokinase)IBA
04/2020 - 12/2016
2CytokinesIBA
02/2020 - 08/2016
2Interleukin-6 (Interleukin 6)IBA
03/2019 - 05/2013
2CollagenIBA
03/2019 - 07/2002
2Cadherins (E-Cadherin)IBA
03/2019 - 09/2011
2corydalmineIBA
01/2019 - 01/2018
2Dynamins (Dynamin)IBA
01/2019 - 01/2017
2SolutionsIBA
11/2018 - 01/2017
2Nonmuscle Myosin Type IIAIBA
11/2018 - 01/2016
2Interleukin-8 (Interleukin 8)IBA
01/2018 - 06/2008
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2018 - 05/2008
2Hexosaminidases (Hexosaminidase)IBA
09/2017 - 01/2017
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2016 - 04/2013
2Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
09/2011 - 12/2009
2Xylenes (Xylene)IBA
05/2008 - 07/2005
2Ethanol (Ethyl Alcohol)IBA
05/2008 - 09/2005
1Isoleucine (L-Isoleucine)FDA Link
05/2022
1Linoleic Acid (Linoleate)IBA
05/2022
1Glycerophospholipids (Phosphoglycerides)IBA
05/2022
1Leucine (L-Leucine)FDA Link
05/2022

Therapy/Procedure

15Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2022 - 08/2006
5Ligation
01/2019 - 09/2005
5Oral Administration
08/2016 - 09/2005
3Drug Therapy (Chemotherapy)
01/2022 - 02/2016
3Therapeutics
11/2018 - 01/2012
3Intravenous Injections
08/2016 - 01/2012
2Ischemic Postconditioning
12/2021 - 11/2016